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3D-structure annotation in UniProtKB/Swiss-Prot

Documents about 3D-structure annotation in UniProtKB/Swiss-Prot

About UniProt

History and background.

Accession

Provides a stable way of identifying UniProtKB entries

Active site

Amino acid(s) directly involved in the activity of an enzyme

Activity regulation

Description of regulatory mechanisms for enzymes, transporters or microbial transcription factors

UniProtKB advanced search options

List of options available in the "Advanced search" interface.

Using Jalview and Java Web Start

Using Jalview and Java Web Start for alignment results

Allergenic properties

Information relevant to allergenic proteins

Alternative products

Description of the different proteins generated from the same gene

Annotation guidelines

Standard operating procedure, protein naming, protein existence

Annotation score

Annotation scores provide a measure of how much annotation has been associated with a given entry or proteome.

How can I access resources on this website programmatically?
Programmatic access - Batch retrieval of entries

Programmatically retrieve UniProt entries corresponding to a list of UniProt identifers

Programmatic access - Downloading data at every UniProt release

Record release number and date, download at every release and avoid downloading data more than once per release

Programmatic access - Format conversion

Convert UniProt entries between different formats

Programmatic access - Mapping database identifiers

Convert identifiers which are of a different type to UniProt identifiers or vice versa

Programmatic access - Retrieving entries via queries

Programmatically retrieve entries in various formats, via queries

Programmatic access - Retrieving a random entry

How to retrieve a random entry from a given query result

Programmatic access - Retrieving individual entries
Automatic annotation

Enhancing unreviewed UniProtKB/TrEMBL records

Saving proteins with the UniProt basket

Remember your favorite proteins, come back later for alignment, analysis, download etc.

Alex Bateman

Alex Bateman short biography

Binary interactions

Information relevant to binary protein-protein interactions

Why are only a subset of binary interactions from the IntAct database reported in UniProtKB?
Binding site

Binding site for any chemical group (co-enzyme, prosthetic group, etc.)

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